Del301-303 α<sub>2B</sub>AR has a stronger interaction with spinophilin than WT α<sub>2B</sub>AR.
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Abstract
<p>(A) Cells co-expressing Myc-spinophilin together with HA-tagged WT or Del301-303 α<sub>2B</sub>AR were stimulated with 100μM epinephrine (plus 1μM propranolol to block βARs). (B) Quantitation of the agonist-induced fold change of Myc-spinophilin in the IP complex with the WT α<sub>2B</sub> or Del301-303 α<sub>2B</sub>AR. n = 3–5 for each condition. **, <i>p<</i>0.01, WT <i>vs</i>. Del301-303 α<sub>2B</sub>.</p
