Involvement of IGF-1 in the inhibition of migration and invasion by migracin A.

Abstract

<p>A. Inhibition of IGF-1 mRNA expression in ES-2 cells. The cells were incubated with indicated concentration of migracin A for 24 h, and the mRNA was measured by PCR. B. Knockdown of IGF-1 by siRNA in ES-2 cells. C. Inhibition of cellular migration by knockdown of IGF-1. D. Inhibition of cellular invasion by knockdown of IGF-1.</p