Effect of 2-Phenylnaphthalenes PNAP-1−PNAP-8, Their Demethylation Derivatives PNAP-2h−PNAP-7h, and Amino PNAP-8h on the Viability of MCF-7 Cells.
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Abstract
<p>The MCF-7 cell line was treated with <b>PNAP</b>-<b>1</b>−<b>PNAP</b>-<b>8</b>, and <b>PNAP</b>-<b>2h</b>−<b>PNAP</b>-<b>8h</b> at eight concentrations and then incubated at 37°C for 48 h. The cell viability was examined via the MTT assay.</p><p><sup>a</sup> The number of viable cells remaining after PNAP treatment is expressed as a percentage of the vehicle control, which was arbitrarily assigned a value of 100.0%. The results are presented as the means ± SEM from three independent assays.</p><p>*P<0.05 and **P<0.01 compared with the control.</p><p>Effect of 2-Phenylnaphthalenes PNAP-1−PNAP-8, Their Demethylation Derivatives PNAP-2h−PNAP-7h, and Amino PNAP-8h on the Viability of MCF-7 Cells.</p
