EutR in <i>S</i>. Typhimurium niche adaptation.

Abstract

<p>(<b>A</b>) EutR senses ethanolamine to activate transcription. (<b>B</b>) In the intestine, EutR promotes expression of the <i>eut</i> operon that encodes ethanolamine metabolism, thereby enhancing <i>S</i>. Typhimurium growth. (<b>C</b>) EutR expression in macrophages activates expression of genes in SPI-2, which are required for intramacrophage survival and dissemination.</p