Force decomposition profile.

Abstract

<p>(A) Schematic of the forces acting on kinetochore sisters. (B-E) Estimated decomposition of kinetochore velocity into its force components over time for the trajectory in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1004607#pcbi.1004607.g001" target="_blank">Fig 1C</a>; (B, D) sister 1 and (C, E) sister 2. Polymerisation/depolymerisation force on kinetochores attributable to the K-fibre (blue/red, respectively); spring force (green); polar ejection forces (orange) and the total force (purple). Time-series overlaid with inferred end (black dashed) and start (green dashed) times of coherence periods (runs). Between end and start times K-fibres are incoherent (in this case +/+) Note that forces are positive in the anti-poleward direction.</p