Morphological damage in the obstructed kidney (OK, 2B, D, F) compared to the contralateral kidney (CL, 2 A, C, E).

Abstract

<p>All OK kidneys show tubular dilatation, flattened tubular epithelium with loss of brush border and reactive nuclear enlargement. Only Mmp2+/+ OK (2B) shows necrotic tubules (asterix) and many apoptotic cells (arrows). The morphology of the CL kidney is normal. (PAS stain).</p