<p>Cells were treated with different concentrations of MEL-A for 24 h. (a) ~ (f) refer to the cell population changes of B16 treated by 0, 6.0, 9.0, 12.0, 15.0, 25.0 μg/mL MEL-A, respectively. Most MEL-A-induced cells were evident in B2 fraction, and the tendency of the induced cells apoptosis was in a dose-dependent manner. Mean ± SD, n = 3.</p