A copper-catalyzed novel carbene/alkyne
metathesis cascade reaction
with alkyne-tethered diazo compounds is described. The whole transformation
features a dual-functionalization of alkyne to install one CN
and one CC bond on each carbon with azide and diazo groups,
respectively, in one reaction, which represents a practical synthetic
alternative to the multisubstituted 4-carboxyl quinoline derivatives
and with most of them in high to excellent yields
