Fast and Protecting-Group-Free Synthesis of (±)-Subincanadine C
- Publication date
- Publisher
Abstract
The first total synthesis of (±)-subincanadine C has been accomplished in a protecting-group-free fashion. This pentacyclic indole alkaloid was synthesized in six steps from the known intermediate <b>4</b>, featuring Ni(COD)<sub>2</sub>-mediated intramolecular Michael addition as a key transformation