Post-stroke shoulder pain (PSSP) is traditionally regarded as a peripheral nociceptive pain. However, treatment aimed at peripheral pain mechanisms is often unsatisfactory and pain is persistent in a significant amount of patients. In addition, several signs of central sensitization (allodynia, generalized hyperalgesia) have been observed in patients with chronic PSSP, suggesting that central pain processing may be altered in these patients. To better understand the role of peripheral and central mechanisms in the development of PSSP we investigated pain complaints and somatosensory functions at baseline and two consecutive follow-up time frames
