<p>(a) MRI of a 58-year-old female showed an invasive ductal carcinoma on the upper outer quadrant of the left breast. The green circle indicates the region of interest (ROI) that was used for estimating the change in the C1 value, and the red circle represents the ROI for measuring the ΔM. (b) The blue line is the time-signal intensity curve, and the orange line was generated from a plot of the C2 values to form a kinetic modeling curve.</p
