Disorganization and degeneration of hair bundles in <i>Tur/Tur</i> mutant cochleae at P0 and P21.

Abstract

<p>SEM images showing stereocilial bundles of outer hair cells in the mid-basal turn in wild-type at P0 (A) and P21 (E), <i>Tur/Tur</i> at P0 (B-D) and P21 (F,G). <i>Myo6</i>^{<i>Tur/Tur</i>} cochleae show misshapen stereocilia, which appear to be smaller/narrower when compared to those in wild-type mice at P0. At P21, stereocilial degeneration is apparent in the majority of cells in the mid-basal turn (arrows). Scale bars: A-D, 2 μm; E,F, 3.0 μm; G, 2.5 μm.</p