Correlation analysis of plasma AC species and amino acids with the degree of obesity and insulin resistance.

Abstract

<p>Plasma levels of individual metabolites assessed in both male and female mice (M and F, respectively) at week 4 and 22 were correlated with the parameters of body weight gain during a 12-week period of high-fat feeding (i.e. week 12–24; <b>A</b>) and with the change in insulin sensitivity during a 10-week-period (i.e. week 12–22; <b>B</b>). Data are presented as heatmaps, where different colors correspond to coefficient values of the respective correlations (Spearman's rank correlation coefficients).</p