<p><b>(H&E)</b> a) Distal metaphysis exhibiting trabecular destruction, necrosis, and replacement fibrosis throughout regions of previous tumor burden. The growth plate (asterisk), metaphysis (dagger), and epiphysis (double dagger) are shown for reference. (20x) Note the metaphyseal tumor does not cross the growth plate to the epiphysis, where normal trabecular architecture is evident. b) Loosely organized fibrous connective tissue and necrosis in tumor-burdened areas. (100x).</p
