<p>A. Representative immunoblots showing that AICD-Tg mice at 3–4 months of age have increased pY1472-NR2B (pNMDAR) levels to total NMDAR levels compared to age-matched non-transgenic animals. B. Lack of tau normalizes the increased pNMDAR levels in AICD-Tg animals. C. Quantification of pNMDAR/NMDAR levels in wild-type and AICD animals in the presence (Tau +/+) or absence (Tau-/-) of tau. n = 5–6 for each genotype. *p<0.05, **p<0.01, ***p<0.001 one way ANOVA (Mean ± SEM).</p
