<p>(a) First, the sense of residue twist changes from right-handed (‘D’) to left-handed (‘L’) as one moves from the bottom left of the Ramachandran plot to the top right. Second, contours (colored) of end-to-end polymer distance <i>R</i><sub>e</sub> (here calculated for a 20-residue glycine) have a negative slope, resulting in the general trend shown in panel (b). Panel (c) indicates one method of indexing the Ramachandran plot so as to move from the region of right-handed twist to the region of left-handed twist with <i>R</i><sub>e</sub> changing as slowly as possible. This method provides the basis for the construction of the Ramachandran number, .</p