Schema for the lung cancer case cohorts in the NLST at prevalence (baseline) and incidence screening (follow-up) rounds.
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Abstract
<p>Abbreviations: T0 = baseline screen; T1 = first screen; T2 = second screen; [+] = positive screen; [–] = negative screen. Prevalence lung cancers diagnosed at T0 are shaded green. Screen-detected lung cancers diagnosed at T1 and T2 rounds in which T0 screens were positive are shaded blue. Screen-detected lung cancers diagnosed at T1 and T2 in which T0 screens were negative are shaded red. Interval cancers (beige boxes) were diagnosed following a negative screen. Participants were excluded if their screening results were inadequate or not compliant. At baseline we excluded 413 screens, 1,471 screens at T1, and 713 screens at T2.</p