Illustrative model demonstrating how the Bacille Calmette Guérin (BCG) vaccine might drive interleukin (IL)-12 p35 and p40 (IL-12 p70) production and CD4+ T-cell T-helper 1 (Th1) polarization in neonates.

Abstract

<p>IFN = interferon; cDC = conventional dendritic cell; NK = natural killer; pDC = plasmacytoid dendritic cell; TLR = Toll-like receptor.</p