<p>A549 (A-C), H460 (D) or primary human lung cancer cells (“Pat-1/-2”) (D), as well as the lung epithelial BEAS-2B cells (D) and human HL-7702 hepatocytes (E) were treated with applied concentration of ONC201 for indicated time, cells were subjected to MTT assay (A, D and E), colony formation assay (B) and LDH release assay (C). The results presented were representative of three independent experiments. The values were expressed as the means ± SD. “C” stands for untreated control group. *<b><i>p</i></b><0.05 vs “C” group.</p