In this report, we describe the generation
of remote allylic quaternary
stereocenters β, γ, and δ relative to a carbonyl
in high enantioselectivity. We utilize a redox-relay Heck reaction
between alkenyl triflates and acyclic trisubstituted alkenols of varying
chain-lengths. A wide array of terminal (<i>E</i>)-alkenyl
triflates are suitable for this process. The utility of this functionalization
is validated further by conversion of the products, via simple organic
processes to access remotely functionalized chiral tertiary acid,
amine, and alcohol products
