Phylogenetic analysis based on clock and cycle/Bmal sequences.

Abstract

<p>The tree was generated by Maximum Likelihood method using Mega 6 program and based on the multiple alignments performed with Clustal Omega. Percentage of bootstraps based on 1,000 replicates were indicated with only values > 50%. Hypoxia-inducible factor (HIF) from <i>C</i>. <i>gigas</i> was used as outgroup to root the tree. See <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0169790#pone.0169790.s004" target="_blank">S2 Table</a> for sequence details and accession numbers.</p