<p>We assess the degree of recovery of dual TCR<i>α</i> clones with the ‘adjusted depth,’ which is the proportion of dual TCR<i>α</i> clones correctly assigned out of the list of candidate dual TCR<i>α</i> and TCR<i>β</i>-sharing clones. Panel (A) shows the adjusted depth of common clones; panel (B), rare clones. For common clones, we used likelihood-based discrimination; for rare clones we used a clustering approach. Both procedures are detailed in Methods. Panel (C) shows the false dual rate averaged over all clones—the proportion of identified dual TCR<i>α</i> that are incorrect. All results are shown for a threshold of 0.3 with 30% prevalence of dual TCR<i>α</i> and are averages over 100 simulations.</p
