Performance outcomes of clinical TB diagnosis and Xpert MTB/RIF using culture as reference standard for patients <15Â years old and referred for presumptive TB. The data in additional file 1 shows the sensitivity, specificity, PPV and NPV of clinical TB and Xpert MTB/RIF compared to culture as the reference standard for all patients as well as the subgroups of inpatients, outpatients, HIV positive and HIV negative. (DOCX 12 kb