<p>(A) Agreement between Monte-Carlo simulation and theory, plotted based on conditions in the paramacular RPE of a healthy 20-year old person. The optical density (OD) was calculated based on the product of the attenuation coefficient and the melanosome layer thickness (<i>l</i><sub>melanin</sub>). Attenuation by absorption (striped line), scattering (dotted line), and total attenuation (straight line) are plotted separately. The MC results are shown in blue (left Y-axis) and the theoretical result is shown in red (right Y-axis). See text for details. (B) Simulations of a thin (3 μm; blue) and thick (52.5 μm; orange) layer of melanosomes. In case of thicker layers, there is a dominance of the absorption coefficient (<i>μ</i><sub><i>a</i>, melanin</sub>, straight lines) over the backscattering coefficient (<i>μ′</i><sub><i>s</i>, melanin</sub>, striped lines) for all tested wavelengths.</p
