A neural network model of L4 explains suppression of whisker movement signals in L4 excitatory neurons.
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Abstract
<p>The colors black, grey and red denote T, L4E and L4I neuronal populations respectively. <b>(a)</b> Example L4E and L4I membrane potential during simulated whisking (green). <b>(b)</b> The population- and time average spike rates ν<sub>E</sub> and ν<sub>I</sub> of the L4E and L4I neurons respectively as function of the thalamic input <i>A</i><sub>T</sub> in the absence of touch. L4I neurons follow linearly the thalamic input while L4E neurons increase only weakly with <i>A</i><sub>T</sub> beyond firing threshold. Inset, zoom in. <b>(c)</b> Membrane potential for an example neuron during whisking and touch (black dots). <b>(d)</b> Population PSTH aligned to touch onset. Inset, zoom in.</p