Number of experimentally verified circRNAs detected by each method.

Abstract

<p>A total of 282 experimentally verified circRNAs were manually compiled from 17 studies, and the number of circRNAs rediscovered by each method on HeLa and Hs68 RNase R–treated samples was computed. CircRNAs with ≥1 and ≥2 supporting reads are shown in light blue and deep blue color, respectively. GE1: candidates with greater than or equal to 1 supporting reads; GE2: candidates with greater than or equal to 2 supporting reads. circRNA, circular RNA; RNase R, exonuclease that digests linear RNAs but preserves circRNAs.</p