Immobility time of NrbKO and SpKO mice in FST at 11–13 months of age (middle-aged).

Abstract

<p>(A) Immobility time (in sec) in each trial for age- and strain-matched WT (n = 8) and neurabin KO (n = 8) mice tested in parallel. (B) Immobility time in each trial for age- and strain-matched WT (n = 9) and spinophilin KO (n = 9) mice tested in parallel. Data are mean ± SEM. **, <i>p</i><0.01, NrbKO <i>vs</i>. WT; ****, <i>p</i><0.0001, SpKO <i>vs</i>. WT by post hoc Sidak's multiple comparison test following two-way ANOVA.</p