Additional file 2: Figure S1. of Developmental disruption of amygdala transcriptome and socioemotional behavior in rats exposed to valproic acid prenatally
RNA sequencing pathways differentially altered across development between VPA and saline amygdala. Pathways with significant time (P10–21) by treatment (VPA/saline) effects are displayed. Treatment effects did not reach statistical significance after FDR multiple comparison correction, thus Ingenuity Pathway Analyses were run on genes with uncorrected p < 0.05 treatment effects at P10 (n = 542) and P21 (n = 406). Canonical pathways and diseases and functions categories with predicted activation or inhibition differences were broadly categorized into the following groups: cellular development and growth; nervous system development and function; immune system, cancer, disease; cell/organismal death; metabolism; and developmental, neurological, or psychological disorder. (PDF 59 kb
