Top 20 significant canonical pathways of the core analysis in IPA (Ingenuity) of most highly expressed genes of the IE and the RPE.

Abstract

<p>P-values indicate the significance of enrichment for the most highly expressed genes from our dataset. P-values were corrected for multiple testing using the Benjamini-Hochberg (B-H) false discovery rate. The upper graph (light blue bars) represents the–log(B-H) p-value of the RPE and the lower graph (dark blue bars) represents the–log(B-H) p-value of the IE. The orange line indicates the threshold of B-H corrected p<0.001.</p