Showing the effect of 5-HT6 on cilia length in excitatory and inhibitory neurons. (A) 5-HT6 regulated cilia length in excitatory neurons. 5-HT6 indicated cilia. CamkII was the marker of excitatory neuron. (B) Overexpression of 5-HT6 increased cilia length. siRNA of 5-HT6 reduced cilia length. 5-HT6, ***p < 0.001; 5-HT6 siRNA, *p < 0.05 (Kruskal–Wallis test, p < 0.001). (C) 5-HT6 regulated cilia length in inhibitory neurons. Gad was the maker of inhibitory neuron. 5-HT6 indicated cilia. (D) Cilia length increased by overexpression of 5-HT6 and decreased by siRNA of 5-HT6. 5-HT6, ***p < 0.001; 5-HT6 siRNA, *p < 0.05 (Kruskal–Wallis test, p < 0.001). Scale bars, 10 μm. All data presented as mean ± SEM. (DOC 4724 kb
