The place of sperm DNA fragmentation testing in current day fertility management

Abstract

In this debate article, I am going to set out the case that sperm DNA fragmentation testing is essential in current day fertility management because- • Our current semen analysis testing is unfit for purpose • Sperm DNA damage testing has strong associations with every fertility check point • Sperm DNA damage testing has strong associations with miscarriage • Sperm DNA testing can explain ‘unexplained’ infertility • There are reasons why sperm with poor DNA are successful in ICSI • There are no non-invasive sperm function tests that provide the same information • We need to take a fresh look at the ‘evidence’ against sperm DNA testing • We have no reason to wait. There are benefits for clinics and couples alike