AbstractIt has been acknowledged that megalopolises are playing a leading role in the processes of both economic development and culture change. Thereupon, the new emphases on sustainability of transportation system in megalopolis are creating new demands for adequate approach to measure its performance and diagnosis potential drawbacks. By examining the descriptions of sustainable transport system as well as its evaluating approach, a framework with the general applicability and easily accessible data resource for evaluating sustainability of transport system in megalopolis is developed based on nature of regional structure and the feature transport demand in megalopolis. The proposed framework is applied in the analysis and comparison of Jing-Jin-Ji and Yangtze River Delta.