Pneumonije su jedna od najtežih komplikacija KOPB-a i ujedno jedna od najčešćih infekcija u bolesnika s njime, koja znatno pridonosi pogoršanju osnovne bolesti. Upale pluća u bolesnika s KOPB-om pokazuju određenu specifičnost u odnosu prema općoj populaciji ne samo u pogledu najčešćih uzročnika, simptoma bolesti i razine upalnog odgovora već i duljine liječenja i terapijskog pristupa. Pneumonije u bolesnika s KOPB-om treba pravodobno dijagnosticirati i liječiti te razlikovati od akutnih egzacerbacija KOPB-a, a unatoč tomu što dovode do težega kliničkog tijeka i duljeg liječenja s češćim hospitalizacijama ne utječu znatno na ukupni mortalitet bolesnika s KOPB-om.Pneumonia is one of the most severe complications of COPD and also one of the most common infections in COPD patients, contributing significantly to the worsening of the underlying disease. Compared to the general population, pneumonia in COPD patients is differentiated not only by microbial etiology, clinical presentation and the level of the inflammatory response, but also by the length of treatment and the therapeutic approach. Pneumonia in COPD patients should be diagnosed and treated on time and it should be differentiated from the acute exacerbation of COPD in terms of baseline severity, microbiology, and inflammatory pattern. Despite worse clinical presentation and lengthier treatment with more frequent hospitalisations, the mortality rate of COPD patients is similar to that of non-COPD patients