Building on automatic text analysis, this paper proposes an original categorization of Research and Innovation Smart Specialisation Strategy (RIS3) priorities and provides a common language (with detailed dictionaries) to classify priorities and then to associate EU regions to multiclass categories of priorities. This result is a powerful tool to interpret the current state of diversification across regions, with its potential of complementarities and synergies that might support territorial integrated development paths. It would also support regions in their future strategic programmes on RIS3. A case study on the Alpine macro-region shows innovation development paths to outline macroregion strategic planning