Patient progress modelling and results in Wilm's Tumour

Abstract

The report describes the development of a mathematical model of the progress of patients with Wilm's Tumour using the methodology developed by Jackson & Aspden [1, 2]. The model incorporates two prognostic factors which are shown to influence patient progress. These are the stage of the tumour and the age of the patient at presentation. The model proved adequate to represent an initial set of patient data, and comparison runs were performed with data from a later time period. These runs highlighted changes in patient progress between the two groups and illustrated the usefulness of the model in this type of analysis. The analysis also underlined the poor prognosis of patients over 5 years old who relapsed.