Eighty-three patients with bipolar affective disorder and 96 controls were studied for genetic association with Msp I restriction fragment length polymorphism in the serotonin 2A receptor gene. No significant association between bipolar affective disorder and the serotonin 2A receptor gene polymorphism was found. This result contradicts the hypothesis that the serotonin 2A receptor gene plays a role in the genetic predisposition to bipolar affective disorder.departmental bulletin pape
