Nucleotide and deduced amino acid sequence of BSFL CTSL.

Abstract

The dotted line indicates the putative signal peptide sequence (Met1-Ala16), and the putative mature domain is underlined (Pro175-Pro337). The triad of conserved catalytic active sites (Cys146, His285, and Asn306) is in circled frames, and Gln140 of the oxyanion hole is in the diamond frame. Five S2 subsites are defined by residues Leu190, Met191, Ala257, Leu283, and Gly286 and indicated by the square frames. The asterisk marks the stop codon at the end of the open reading frame.</p