Comparison of <i>c</i>(<i>s</i>) distributions computed with the command line initialization of SEDFIT and with manual operation.

Abstract

The distribution from command line operation (Fig 2), and exhibits a monomer peak at 6.477 S with 29.20% of signal, a trace degradation product at 4.199 S with 0.95% of signal, a dimer peak at 9.473 S with 12.51% of signal, and higher aggregates with collective sw 16.799 S and 51.77% of signal. The analogous manually operated analysis producing a monomer peak at 6.481 S with 29.27% of signal, a degradation product of 4.178S with 0.92% of the signal, a dimer peak at 9.488 S with 12.51% of signal, and higher aggregates with collective sw of 16.81 S with 51.73% of signal. Integration and plot were made using the software GUSSI [59], which can be spawned from the script mlSEDFIT.</p