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The fitting result and Probabilistic distributions of the estimated parameters using approximate Bayesian computation schemes involving the simulated likelihood density for the pathway with <i>APC</i><sup>+/−</sup> → <i>APC</i><sup>−/−</sup> → <i>KRAS</i><sup>+</sup> → <i>TP</i>53<sup>+/−</sup> → <i>TP</i>53<sup>−/−</sup>.

Abstract

(a) (NμN of model), (b) ( of model), (c) ( of model), (d) ( of model), (e) ( of model), (f) The colorectal cancer incidence rate per 100,000 patients from SEER registry and rates predicted by the model.</p

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