Co-localization between HEALS DMA% association signal (rs4919687) and <i>AS3MT</i> eQTLs in the Liver.

Abstract

a. We detect AS3MT eQTLs in the liver and observe evidence of co-localization (Panel A), but this evidence was not consistent across all sets of priors analyzed. The low efficiency (low DMA%) allele at rs4919687 is associated with lower AS3MT expression in the liver, though this pattern is observed more strongly in other tissue types (Panel B). (PDF)</p