Additional file 3 of Macrophage polarization toward M1 phenotype through NF-κB signaling in patients with Behçet’s disease

Abstract

Additional file 3: Supplemental Figure S1. Representative FACS plot depicts the purity of monocytes, macrophages and naïve T CD4+T cells. Supplemental Figure S2. MFI analysis of BD serum-promoted macrophage polarization. Supplemental Figure S3. BD serum promotes CD86+CD163-CD206- M1-like macrophage polarization. Supplemental Figure S4. BD serum-treated macrophages facilitate Th1 differentiation under Th0 condition. Supplemental Figure S5. MFI analysis of T-bet in BD serum-treated macrophages. Supplemental Figure S6. BD serum-treated macrophages facilitate Th17 differentiation. Supplemental Figure S7. BD serum-treated macrophages produced more CXCL2 and CXCL3. Supplemental Figure S8. NF-κB inhibition attenuated CD86 expression on macrophages stimulated by BD serum. Supplemental Figure S9. Activated JAK/STAT pathway in BD serum-treated macrophages