The table shows the list of <i>Homo sapiens</i> genes, prioritized in skin tissue, using the Human Protein Atlas database (https://www.proteinatlas.org/).

Abstract

In order to prioritize skin genes, we selected those with higher expressions from the skin-enriched genes list of the Human Protein Atlas database (https://www.proteinatlas.org/search/tissue_specificity_rna:skin;Tissue enriched+AND+sort_by:tissue+specific+score+AND+show_columns:groupenriched). All data (RNA, TS, TPM, Protein expression scores and Tissue specificity) were also obtained by the Human Protein Atlas database. *RNA TS TPM indicates RNA level reported as mean TPM (transcripts per million), in referred tissue, skin in this case. **Protein expression scores are based on a best estimate of the "true" protein expression from a knowledge-based annotation in the selected tissue, skin in this case. ***Tissue specificity is based on data found in the graph called “HPA tissue dataset”, a sub-category of the “RNA sample summary” section in the HPA site, for each gene. The RNA summary section shows normal distribution of individual samples across the datasets of multiple RNA-seq analyses visualized with box plots. “Only” is used for a gene transcript present only in the specific tissue (skin). “Predominantly” is used when the majority of a gene transcript is present in the specific tissue (skin). “All” is used for a gene transcript present in all tissues. (DOCX)</p