Additional file 8 of Integration of genetic, transcriptomic, and clinical data provides insight into 16p11.2 and 22q11.2 CNV genes

Abstract

Additional file 8: Table S7. Conditional analysis for independence of associations. Conditional analysis was performed on the PGC schizophrenia data, the UK Biobank BMI data, as well as two BioVU clinical trait associations (16p11.2 genes and psychosis, 22q11.2 genes and morbid obesity). For each trait, we performed MultiXcan first adjusting for a specific gene, then by leaving a gene in and adjusting all the other genes associated with that trait out. The Pcond reported in the text is the p-value of this gene-trait pair when adjusting for all other genes considered for conditioning for this trait, unless otherwise stated