Phosphorylation of S338 of c-Raf is reduced by NECA and forskolin.

Abstract

A time-dependent inhibition of phosphorylation of c-Raf at S338 is observed by stimulation of the A2B receptor with NECA (A). A similar effect was seen with forskolin (B). Western blots show a representative experiment, the columns represent mean values from n = 5 (A) and 10 (B) independent experiments (* p < 0.001, significantly different from control).</p