Reduction of ERK1/2 phosphorylation by UTP compared to NECA.

Abstract

The effect of 100 μM UTP was consistently lower than of 100 nM NECA. Addition of 30 nM forskolin to 100 μM UTP increased the UTP effect although forskolin at this concentration had no effect on its own. The Western blot shows a representative experiment, the columns represent mean values from from n = 7 independent experiments (* p < 0.001, significantly different from control; # p < 0.05, significantly different from each other).</p