Effect of metformin on IL-6-induced STAT3 phosphorylation and <i>MMP9</i> expression in the human colon cancer cell line COLO 205.

Abstract

(A) Western blot analysis of metformin- and IL-6- treated colon cancer cells (HCT 116). (B) Western blot analysis of metformin- and siRNA STAT3 (siSTAT3)—treated colon cancer cells (HCT 116) (C) qPCR analysis of metformin- and IL-6-treated colon cancer cells. Fold-, fold-change; Met, metformin. *p p < 0.01.</p