(A) Fib3-1, (B) Fib3-2 and (C) Fib3-3 levels found in osteoblasts cell culture supernatant. Data are means +/- SD from 4 patients for Fib3-1, 7 patients for Fib3-2 and 9 patients for Fib3-3. Comparisons of mean values were performed by paired t-test.</p