Dramatic Effects of Ionic Liquids on the Palladium-Catalyzed Cyclocarbonylation of Enynols with Thiols

Abstract

Palladium-catalyzed carbonylation reactions of enynols with thiols in ionic liquids afford monocarbonylated 6-membered-ring lactones in high yields and good selectivity. These results are significantly different from those obtained when conducting the reaction in THF. The recyclability of the catalytic system was also investigated