Copper-Catalyzed Enantioselective Substitution of Allylic Carbonates with Diboron:  An Efficient Route to Optically Active α-Chiral Allylboronates

Abstract

A method for the synthesis of α-chiral allylboronates featuring the Cu(I)-catalyzed enantioselective substitution of readily available allylic carbonates with a diboron is described. Using this method, various α-chiral allylboronates, including functionalized allylboronates, were successfully synthesized, with high enantiomeric purity