A20 controls maturation and cytokine production of Mф.

Abstract

<p><b>A</b>. Expression of costimulatory molecules and MHC class II molecule on the adenoviral-transduced BMMф in response to stimulation of LPS. <b>B</b>. Production of inflammatory cytokines by the adenoviral-transduced BMMфs, as tested by ELISA. <b>C</b>. NO production by adenoviral-transduced BMMфs, as tested by Griess assay. Experiments were repeated three times with similar results. *p<0.05, **p<0.01 Ad-shA20- vs. Ad-con-transduced Mф.</p